No idea what is specifically causing the problem (although I'll bet you anything that the iTunes problem is a side-effect of the botched 10.4.6 update), but I can at least make some suggestions for finding out:
In the "Utilities" folder, there's a "Console" app. Open it up: hey look, syslog!
You might want to try running the combo app installer from the command line, and see if it's spitting out any useful diagnostics there while it's failing to see your hard drive. OSX application bundles are represented by icons in the finder, but are actually just directories when you look at them in the shell: the actual executable will be under DIRNAME/Contents/MacOS/.
Last but not least, you could try re-installing the 10.4.5 combo update, but that's serious voodoo/make-backups-first territory.
And of course, you can try contacting apple support. :)
no subject
No idea what is specifically causing the problem (although I'll bet you anything that the iTunes problem is a side-effect of the botched 10.4.6 update), but I can at least make some suggestions for finding out:
In the "Utilities" folder, there's a "Console" app. Open it up: hey look, syslog!
You might want to try running the combo app installer from the command line, and see if it's spitting out any useful diagnostics there while it's failing to see your hard drive. OSX application bundles are represented by icons in the finder, but are actually just directories when you look at them in the shell: the actual executable will be under DIRNAME/Contents/MacOS/.
Last but not least, you could try re-installing the 10.4.5 combo update, but that's serious voodoo/make-backups-first territory.
And of course, you can try contacting apple support. :)