in this rpg...

[rone]

The PCs are magical doctors in New England who, with magic, fight terrorists for gold in the Renaissance.

Try it yourself and see what you get.  Authored by legomancer.

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[dnereverri.livejournal.com]

"The PCs are Japanese rebels in a large corporation who, with the power of music, fight zombies for God and country in the present day."

Wait, I think I've read that manga...